Brain & Mood Optimization

Your Brain Runs On
3 Key Neurotransmitters.
Support All Three, Naturally.

One ancient spice — studied in peer-reviewed research 3 times over — may support dopamine, serotonin, and norepinephrine pathways simultaneously.*

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The Big Picture

Your Mood Is Chemistry

Hover or tap each card to unlock the deep science on each neurotransmitter.

🧠 Your Brain
⚡Dopamine
🌊Serotonin
🔋Norepi
⚡
Dopamine
Drive & Reward
Motivation · Focus · Pleasure · Goal pursuit
⚡ Dopamine - Deep Dive
  • Made from tyrosine. Needs B6, magnesium & iron to synthesize
  • Everyday factors like poor sleep, stress, and diet can affect dopamine activity over time
  • Lifestyle habits that support dopamine: cold showers, exercise, sunlight, protein-rich meals
  • Saffron crocins may support dopamine activity in the brain — extending its active signaling time*
  • Research suggests consistent daily support over 4-8 weeks for best results*
🌊
Serotonin
Calm & Contentment
Mood stability · Well-being · Sleep quality
🌊 Serotonin - Deep Dive
  • ~90% made in your gut, not your brain. Gut health = serotonin health
  • Requires tryptophan + B6, folate & zinc to synthesize
  • Everyday factors like stress, inflammation, and diet can affect serotonin pathways over time
  • Natural supports: sunlight, tryptophan-rich foods (turkey, eggs, cheese), probiotics
  • Safranal in saffron may interact with serotonin receptors to support healthy mood balance*
🔋
Norepinephrine
Energy & Alertness
Sharp thinking · Resilience · Stress response
🔋 Norepinephrine - Deep Dive
  • Made from dopamine — supporting dopamine pathways also supports norepinephrine*
  • Controls your "ready state" - attention, alertness, and stress response
  • Everyday supports: aerobic exercise, cold exposure, adequate protein, meditation
  • Chronic stress and poor nutrition can affect norepinephrine balance over time
  • Saffron's bioactives may support all 3 neurotransmitter pathways simultaneously*
By The Numbers

The Depletion Crisis

76%
of adults report chronic stress - dopamine's #1 enemy
1 in 3
people get insufficient sleep, affecting dopamine receptor recovery overnight
4-8hr
daily screen time floods dopamine circuits with micro-hits, affecting natural reward sensitivity
Modern Life vs. Your Brain

4 Silent Depletors

Tap each card to see what's really happening - and what to do about it.

😤
Chronic Stress
Elevated cortisol can directly affect dopamine & serotonin pathways over time*
😤 Chronic Stress
  • Cortisol and dopamine interact — sustained cortisol can affect dopamine signaling
  • Sustained stress may affect areas of the brain involved in mood regulation
  • Chronic stress depletes magnesium — needed to support all 3 neurotransmitter pathways
  • Support: 10 min daily breathwork is associated with reduced cortisol in research
  • Support: Adaptogens (ashwagandha, rhodiola) may help reduce cortisol burden
  • Support: Saffron may support stress-affected serotonin pathways naturally*
😵‍💫
Poor Sleep
Dopamine receptor sensitivity may shift with sleep quality — deep rest matters*
😵‍💫 Poor Sleep
  • Research suggests dopamine receptor sensitivity can be affected by sleep quality
  • Serotonin supports healthy sleep — and quality sleep supports serotonin balance*
  • Deep (slow-wave) sleep is associated with neurotransmitter receptor recovery
  • Support: Prioritizing 10pm-2am sleep window may support overnight restoration
  • Support: Magnesium glycinate before bed may support serotonin-to-melatonin conversion
  • Support: Saffron may support serotonin pathways that contribute to healthy sleep quality*
📱
Overstimulation
Constant micro-hits may affect reward circuit sensitivity over time*
📱 Digital Overload
  • Each notification = a small dopamine signal. Frequent repetition may affect receptor sensitivity over time
  • Reduced receptor sensitivity means natural rewards feel less impactful — a form of tolerance
  • Research suggests this pattern has neurological parallels to tolerance mechanisms
  • Support: "Dopamine reset" - 24hr reducing social media, alcohol, and junk food
  • Support: Replace micro-hit habits with macro rewards (nature, exercise, creating)
  • Support: Saffron may help support receptor sensitivity during reset periods*
🍔
Poor Nutrition
Dopamine needs tyrosine. Serotonin needs tryptophan. Most diets fall short.*
🍔 Nutritional Gaps
  • Dopamine precursor: L-Tyrosine (chicken, eggs, almonds, avocado)
  • Serotonin precursor: L-Tryptophan (turkey, oats, pumpkin seeds, cheese)
  • Cofactors needed: B6, B12, folate, iron, zinc, magnesium, Vitamin D
  • Ultra-processed food causes gut inflammation, which may affect serotonin production
  • Support: Eating protein at breakfast may help set neurotransmitter tone for the day
  • Support: Saffron works alongside a balanced diet to support neurotransmitter pathways*
🌿
Taking a Weed T-Break? Your Brain May Benefit from Extra Support
A tolerance break is a period when your receptors recalibrate. This is a window where nutritional support for your neurotransmitter pathways matters most - and where saffron's peer-reviewed research becomes especially relevant. The cards above show you what lifestyle steps to take alongside supplementation.*
The Science

Why Saffron Works

Peer-reviewed research at 28-30mg daily. Tap each mechanism to see the full picture.*

🔄
Supports Signaling
Crocins may support dopamine & serotonin activity — helping them remain active longer in synapses*
🔄 Neurotransmitter Support
  • After a neurotransmitter fires, it is reabsorbed quickly — a process called reuptake
  • Crocins may support dopamine & serotonin signaling by slowing this reabsorption process*
  • This is a botanical mechanism studied in peer-reviewed research — distinct from pharmaceutical approaches
  • Effect builds over 4-8 weeks of consistent daily use*
  • Full-spectrum extract needed - isolated crocins alone are less effective*
🛡️
Protects Neurons
Antioxidants may help preserve brain cells responsible for neurotransmitter production*
🛡️ Neuroprotection
  • Oxidative stress can affect dopaminergic neurons over time
  • Saffron's carotenoids are among the most studied natural antioxidants
  • May help support neurons involved in dopamine production*
  • Research shows reduced neuroinflammation markers with supplementation*
  • This is long-term brain health support, not just a short-term mood boost*
🎯
Receptor Support
Safranal may interact with serotonin & GABA receptors to support calm, balanced mood*
🎯 Receptor Interaction
  • Safranal has demonstrated affinity for serotonin receptors in peer-reviewed research*
  • GABA receptor interaction may contribute to a calm-without-sedating effect*
  • Unlike sedatives, saffron supports calm alertness - not drowsiness
  • May help support receptor sensitivity back toward normal ranges*
  • Particularly valuable during any receptor recalibration period*
⚖️
Works Naturally
Supports your body's own systems - not forcing changes, supporting them*
⚖️ Botanical vs. Pharmaceutical
  • Saffron works with your body's natural neurotransmitter systems, not against them*
  • No known serotonin syndrome risk at studied doses
  • Does not suppress your own production - supports it instead*
  • Well-tolerated in research at 28-90mg daily with minimal side effects*
  • Safe to use alongside lifestyle changes for a comprehensive approach*
Active Compounds

3 Bioactives. 1 Flower.

🟡
Crocins
Dopamine & serotonin pathway support
🟡 Crocins
  • Water-soluble carotenoids - the pigments that make saffron golden
  • Cross the blood-brain barrier - rare for plant compounds
  • May support dopamine & serotonin signaling by slowing natural reabsorption*
  • Potent antioxidants - may help protect dopaminergic neurons from oxidative stress*
🌸
Safranal
Serotonin & GABA receptor interaction
🌸 Safranal
  • The volatile aromatic compound - responsible for saffron's distinct scent
  • May interact with serotonin receptors to support natural mood balance*
  • Also studied for interaction with GABA receptors — supporting calm without sedation*
  • Converts from picrocrocin during processing - quality processing matters
🔬
Picrocrocin
Precursor to safranal. Signals extract quality.
🔬 Picrocrocin
  • Gives saffron its characteristic bitter taste - a marker of purity
  • Hydrolyzes into safranal during processing and digestion
  • High picrocrocin = high-quality saffron = more safranal bioavailability
  • Why full-spectrum extracts outperform isolates - all 3 work as a system*
What to Expect

Your 12-Week Journey

1-2WKS
Foundation Building
Crocins begin accumulating in tissues. Most people notice nothing yet - that's normal. Take with food containing healthy fat for best absorption.*
3-4WKS
Early Signals
Receptor sensitivity begins shifting. Common early reports: better sleep quality, less morning irritability, tasks feeling slightly less effortful.*
8-12WKS
Full Support
Peak research benefit window. Peer-reviewed studies show meaningful mood support by week 8, with progressive improvement through week 12.*
3X Researched Dose · Full Spectrum

Meet Saffron360™
Your Neurotransmitter Pathways, Supported

88.5mg full-spectrum saffron extract. Dopamine. Serotonin. Norepinephrine. All three pathways, naturally supported.*

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3X Researched Dose Full-spectrum extract No prescription 1-day Prime Shipping
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any supplement.